In 1977, college graduates Harry Burns (Billy Crystal) and Sally Albright (Meg Ryan) share a contentious car ride from Chicago to New York, during which they argue about whether men and women can ever truly be strictly platonic friends. Ten years later, Harry and Sally meet again at a bookstore, and in the company of their respective best friends, Jess (Bruno Kirby) and Marie (Carrie Fisher), attempt to stay friends without sex becoming an issue between them.
John Cusack (Grosse Point Blank), Daphne Zuniga (Spaceballs) and Nicollette Sheridan ("Knots Landing") star in this charming tale of true love that's at once "intelligent, fun, a bit devilish...[and] delightful, frisky and perceptively funny" (The Hollywood Reporter)! College freshman Walter "Gib" Gibson (Cusack) has a "sure thing" going - a date with a very hot and very sex-craved blonde (Sheridan) across the country in LA. Crossed by fate - and the ride-share bulletin board - Gib makes the trip with a studious and abrasive coed (Zuniga).
