Mayim Bialik

The science of funny is back! At work, physicists Leonard and Sheldon and their geek pals conquer the cosmos. At home, real life - from dating to driving - conquers them. This season, Leonard gets a girl. So does Sheldon. (Sheldon?!) Howard drives the Mars Rover into a ditch. Raj woos a terminator. Gorgeous girl-next-door Penny falls under the spell of Age of Conan. And super-smart, überconfident Leslie Winkler reduces mere men to spineless jellyfish.

Physicists Leonard and Sheldon understand everything from the inescapable gravitational pull of a black hole to the intricate structure of the atom. But take those atoms and assemble them into a woman, and their comprehension comes to a grinding halt. And when Penny, a woman with all those atoms in all the right places, moves in across the hall, Leonard and Sheldon's universe begins to expand in ways they never could have imagined.